Migraine Linked to Irritable Bowel Syndrome

Migraine Linked to Irritable Bowel Syndrome

Migraine Linked to Irritable Bowel Syndrome

Our results suggest a high possibility of phenotypic and genotypic associations between IBS and primary headache disorders (particularly migraine) and support the presence of some shared pathophysiology, Derya Uluduz, MD, from Istanbul University in Turkey, told Medscape Medical News.

“Greater attention should be focused on the comorbidities of these conditions and their potential contribution to better understanding and managing the disorder. Physicians should examine the presence of IBS in migraine and tension-type headache patients or vice versa for accurate management of these disorders,” Dr Uluduz added.

Migraine Linked to Irritable Bowel Syndrome
Migraine Linked to Irritable Bowel Syndrome

The study was released February 23 ahead of presentation in April at the American Academy of Neurology 68th Annual Meeting in Vancouver, Canada.

“Migraine of the Bowels”

“In designing this study, we were interested in whether IBS and migraine coexist within a same spectrum of central sensitization syndrome and have phenotypic and genotypic associations,” Dr Uluduz explained. “We already knew that brain plays significant role in IBS. IBS may be characterized by dysfunctions in processing of information by the central nervous system. IBS patients have increased hypothalamic activity suggesting an association among IBS, stress and hypothalamic axis. In this respect, IBS may be defined as the ‘migraine of the bowels.'”

The study included 107 people with migraine, 53 with episodic tension-type headache (ETTH), 107 with IBS, and 53 healthy individuals. “This is the first study to investigate the relationship between IBS and primary headaches, including ETTH, using a comprehensive face-to-face clinical diagnostic evaluation and information on multiple serotonin transporter gene polymorphisms,” Dr Uluduz told Medscape Medical News.

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Inflammatory Bowel Disease

IBS or IBD what’s the difference?

Do you know the difference between IBS and IBD?

It can be tricky, all those Is and Bs, combined with the fact that few of us feel comfortable discussing our bowels normally, let alone if they’re irritable or diseased. So it’s no wonder they can get muddled up in people’s minds.

Here’s our straightforward guide to each: definitions, symptoms to look out for and treatments for both.

IBS – Irritable Bowel Syndrome

What is it?

Affecting the colon and the large intestine, IBS is a term used to encompass a range of gut-related symptoms that cannot be fully explained, or show no direct medical abnormality.

What causes it?

Nobody is quite sure. It is often brought on by psychological triggers such as stress, major life changes and acute anxiety.

However, many also see it purely as a problem with digestion, where your body hasn’t set the right pace for passing food through the gut.

[Related story: 6 top tips to beat irritable bowel syndrome the natural way]

Who gets it?

According to IBS Network: “The quick answer is ‘we all do’, though some people get it more severely than others.” They suggest that 10-20% of people who live in Western countries are suffering from the condition at any one time, but young women and twice as likely to develop it as men and older people.

What are the symptoms?

The condition varies in severity from person to person and can last from a few months up to a lifetime. Symptoms include:

Stomach cramping and spasms
Diarrhoea and constipation
Noisy stomach sounds
Excessive wind
Incontinence and often needing the toilet urgently
Never feeling as though bowels have been fully emptied
Backache and joint pain
Bladder issues
Pain during sex
Anxiety and depression

Read More: IBS or IBD


Irritable Bowel Syndrome Little Evidence for FODMAP Diet

Irritable Bowel Syndrome Little Evidence for FODMAP Diet, There is “very limited evidence” to support a diet low in short-chain carbohydrates, also known as FODMAPs (fermentable oligosaccharides, disaccharides, monosaccharides, and polyols), for patients with irritable bowel syndrome (IBS), according to a review published online August 6 in the Drug and Therapeutics Bulletin.

“Evidence for the efficacy of the low FODMAP diet to improve symptoms of [IBS] is based on a few relatively small, short-term unblinded or single-blinded controlled trials of varying duration,” write James Cave, OBE, FRCGP, editor-in-chief of the Drug and Therapeutics Bulletin, and colleagues, noting that improper use could lead to dietary insufficiencies.

Developed in Australia, the FODMAP diet is based on the premise that patients with IBS have a limited ability to process the small-chain carbohydrates found in wheat, onions, legumes, milk, high-fructose corn syrup, and artificial sweeteners. FODMAP fermentation in the large intestine results in luminal distension, causing pain, bloating, and changes in motility.

Two recent review articles had conflicting conclusions: one concluded there is high-quality evidence supporting the efficacy of low FODMAP diet for IBS, whereas the other “was more cautious in its conclusion,” report Dr Cave and colleagues.

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