Crohns Disease the Effects of Steroids

Just a rant about Prednisone. A sufferer,  I share with not only suffers from her physical situation, but now also the side effects of Prednisone, which for her, are negatively affecting her mind. Why does this bug me me?! Because, now she is suffering with more negative symptoms as a result from the drugs that are meant to be ‘helping’ her with the first set of symptoms. Just in my understanding, something has to have happened (the cause) in order for the consequences to arise (the effect). I.e. An environment has to affect the cells in our body, which in turn creates a change. A negative environment a negative change. Change the negative environment and perhaps a positive change will occur.


First Government Approved Stem Cell Drug for Crohn’s Disease

Columbia biotechnology company Osiris Therapeutics has reached a deal to sell its marquee stem cell drug, the first to win government approval, for up to $100 million.

A subsidiary of Australian company Mesoblast Ltd. has agreed to pay $50 million for the technology behind Prochymal and the drug itself, and Osiris could receive up to $50 million more if the drug passes certain clinical trials and regulatory reviews, the companies said.

Prochymal is being evaluated in a final round of clinical trials for use in treating Crohn’s disease as well as a disorder known as graft versus host disease that can occur after stem cell or bone marrow transplants. Osiris was founded in 1992 to develop stem cell therapies that can be used to stop inflammation and regenerate tissue.

The deal would mean Osiris moving on from what has been its key project for more than 20 years. Company officials said the sale allows them to focus on other projects with potential.


Most People with Celiac Disease Open to Pharmaceutical Treatments 10/17/2013 – A gluten-free diet is till the only treatment for celiac disease, but a number of companies are working on pharmaceutical treatments. However, very little information exists bout the level of interest among patients in using a medication to treat celiac disease.

Image: Wikimedia Commons A research team set out to assess interest levels among patients in medical treatments for celiac disease. The research team included Christina A. Tennyson, Suzanne Simpson, Benjamin Lebwohl, Suzanne Lewis and Peter H. R. Green.

For their study, the researchers submitted a questionnaire to celiac disease patients and collected data on demographics, presentation, and interest in medication. The questionnaire included three validated celiac disease-specific instruments: Celiac Disease Associated Quality of Life, the Celiac Symptom Index, and the Celiac Dietary Adherence Test.