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cancer trials

Poor people aren’t participating in cancer trials

An alarming new report has found that poor people who have cancer are not taking part in critical trials, potentially skewing the results for important new drugs.

The study, which included mostly white women under 65, included 1,200 adult patients who had been diagnosed with breast, lung, or colorectal cancer, found that those whose wages were below average were much less likely to be part of a clinical trial, according to a US News report.

Those who had household income of less than $50,000 per year were a whopping 32 percent less likely than those with higher incomes to participate, and the results get even worse as the household income decreases: just 11 percent of those with household incomes of less than $20,000 per year volunteered to be in a clinical trial.

This is a significant problem facing the medical community. Clinical trial treatments are usually the newest available treatments, and they should be available to those with all income levels.

But more importantly, it could skew the results for important new drugs. Health is actually linked to the amount of income someone has, studies have found, and therefore clinical trials that don’t have poor people participating aren’t likely to get the most accurate results.

In addition, if more poor people were to participate, it might speed up the clinical trial process and therefore get promising new drugs to the public more quickly.

The findings were published recently in the journal JAMA Oncology.

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Ulcerative Colitis

Difference between Colon Cancer and Ulcerative Colitis

The signs and symptoms of colon cancer and ulcerative colitis often confused by many – often leading one to think that a different disease may be present than actually is. However, if these bowel disorders are properly understood as an individual may be able to recognize that there are clear differences from one or another. Nevertheless, it is still important to undergo diagnostic examinations to determine what specific disease is manifested. Below, are images seen through colonoscopy of a healthy, cancerous colon and ulcerative colitis

No one really knows the cause of ulcerative colitis, but it is regarded as an autoimmune disease, which the body’s immune system attacks itself. However, the reaction of the immune system is not only on the body, but it is triggered by the proliferation of yeast known as Candida albicans. Although Candida is a normal flora of the gut once it reaches the large intestines it becomes unwanted residents. The Candida albicans causes severe inflammation of the colon and rectum accompanied by ulcers and open sores.

Read more: The Difference between Colon Cancer and Ulcerative Colitis

 

Surgical resections of ulcerative colitis

Among ten patients who underwent primary operations, four patients had open surgery and six patients had hand-assisted laparoscopic surgery (HALS). Seven patients received anus/anal sphincter-preserving operations with reconstruction by the ileal pouch technique.

Ileal pouch anal-canal anastomosis (IPACA) was performed in five cases and ileal pouch anal anastomosis (IPAA) in two cases. Abdomino-peritoneal resection was performed in two cases, proctcolectomy with permanent ileostomy in one case, and right hemicolectomy in one case. A 39-year-old patient was unresectable due to dissemination of the carcinoma.

A 55-year-old patient who underwent IPACA showed night soiling postoperatively. Other patients who received IPAA and IPACA showed favorable anal function postoperatively. Histological examination showed low-grade dysplasia in two cases, high-grade dysplasia in three cases, and adenocarcinoma in seven cases. In the seven cases of adenocarcinoma, four, two, and one cases were stage 1, 3, and 4 according to TNM classification. Three of five cases with dysplasia were detected by surveillance colonoscopy. All patients with carcinoma were symptomatic and did not undergo surveillance colonoscopy.

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